A class of drugs that are used to treat diabetes seems to help individuals lose weight by altering how the brain reacts to food, according to a new study.
Researchers have been trying to figure out how gut-hormone based medications known as GLP-1 receptor agonists also help individuals with type 2 diabetes lose extra pounds (HealthDay 2015 ).
A Dutch team stated that the drugs may reduce cravings and increase satisfaction while eating. This is good news for many people seeking weight loss but having trouble suppressing their appetite. The researchers looked specifically at the injectable GLP-1 receptor agonist exenatide.
Their discovery will be demonstrated at the American Diabetes Associations (ADA) yearly meeting in Boston on Tuesday. Studies that are presented at meetings are usually viewed as preliminary until they have been published in a peer-viewed journal. With that being said, we cannot jump to any conclusions just yet.
“When you eat, there are several hormones released. GLP-1 is one of them, “Dr. Liselotte van Bloemendaal, a Ph.D. student at the Diabetes Center, VU University Medical Center in Amsterdam, Holland, mentioned in an ADA news release.
“These hormones relay information to the center of the nervous system about nutritional status to regulate appetite. Using working MRI’s (which calculate brain activity by detecting changes in blood flow), we looked at the reward centers in the brains of obese individuals with and without type 2 diabetes and measured the response to the anticipation of and drinking of chocolate milk while being given GLP-1 receptor agonist intravenously versus placebo,” she explained.
When given the drug, the brain did not anticipate the food reward as much. The researchers said this could lead to reduced cravings (HealthDay 2015). The drug also seemed to increase the feeling of reward from food while people were eating, which might reduce overeating, according to van Bloemendaal. I understand that overeating is a major issue for people trying to lose weight and this GLP-1 receptor might be the perfect fat loss tool.
The findings may lead to new treatments for obesity, she said. Van Bloemendaal also wants to determine whether these drugs can reduce cravings for drugs, alcohol and nicotine. If so, people may be able to quit smoking and lose weight at the same time.
Bachelor’s Degree in Criminal Justice
Real Estate Investor & Internet Marketer
Source: Preidt, R. “Certain Diabetes Drugs May Aid Weight Loss by Curbing Cravings” www.healthday.com June 9, 2015